# What are the main medications used to treat rheumatoid arthritis? Canonical page: https://clinicsjo.com/en/faq/what-are-the-main-medications-used-to-treat-rheumatoid-arthritis Language: en Category: medicines Publisher: ClinicsJo Published: 2026-09-13T17:52:53.807Z Content updated: 2026-09-13T17:52:53.807Z Translation (ar): https://clinicsjo.com/ar/faq/what-are-the-main-medications-used-to-treat-rheumatoid-arthritis Treatment for rheumatoid arthritis aims to control symptoms and reduce joint damage, as there is no cure for the disease. The main medications used in treatment include disease-modifying antirheumatic drugs (DMARDs) and biologic therapies, which work to slow the progression of the disease and reduce inflammation and pain [\[1\]](). ## Disease-Modifying Antirheumatic Drugs (DMARDs) Disease-modifying antirheumatic drugs (DMARDs) are the cornerstone of rheumatoid arthritis treatment. These medications work by suppressing the immune system that attacks the body's tissues in the case of rheumatoid arthritis, helping to reduce inflammation and joint damage. Early intervention with these medications is crucial, as it can help prevent the worsening of symptoms and long-term joint damage [\[1\]](). You can learn more about the importance of early intervention in rheumatoid arthritis by visiting [Morning Stiffness in Rheumatoid Arthritis and the Importance of Early Intervention (Arabic)](). It may take several weeks or months for the effects of these medications to become apparent, and patients must adhere to the prescribed dosages and monitor any potential side effects with their treating physician [\[2\]](). ## Biologic Therapies Biologic therapies represent a newer class of drugs that target specific molecules in the immune system that play a role in the inflammation process associated with rheumatoid arthritis. These drugs are typically used when the condition does not respond adequately to conventional disease-modifying antirheumatic drugs (DMARDs) [\[1\]](). These medications are usually administered via injection or intravenous infusion and can be effective in reducing pain and swelling and preventing joint damage [\[1\]](). ## Other Supportive Medications In addition to disease-modifying drugs and biologic therapies, doctors may prescribe other medications to help alleviate symptoms and control inflammation [\[1\]](): - **Nonsteroidal Anti-inflammatory Drugs (NSAIDs):** Used to relieve pain and inflammation. - **Corticosteroids:** Used to rapidly reduce inflammation during severe flares of the disease, but are typically used for short periods due to their potential side effects. ## Important Considerations When Choosing Treatment The choice of appropriate treatment for rheumatoid arthritis depends on several factors, including the severity of the disease, its activity level, the presence of other health conditions, and the patient's response to previous medications. Treatment must be conducted under the supervision of a rheumatologist, who will regularly evaluate the condition and adjust the treatment plan as needed [\[2\]](). It is important for patients to discuss all treatment options with their doctor, including the potential benefits and risks of each medication. Some medications may require regular blood tests to monitor for side effects, such as their impact on the liver, kidneys, or blood counts [\[1\]](). ## Medical references - [Rheumatoid Arthritis]() - [Rheumatoid Arthritis]() General health education; not a substitute for individualized clinical assessment. Citation URL: https://clinicsjo.com/en/faq/what-are-the-main-medications-used-to-treat-rheumatoid-arthritis#answer