
Hyperbaric oxygen therapy for osteitis in Jordan
علاج التهاب العظم بالأكسجين المضغوط
Treating bone infection with hyperbaric oxygen means adding sessions of breathing high-concentration oxygen inside a pressurised chamber to the treatment of chronic osteomyelitis that has resisted correct therapy. Chronically infected bone becomes poorly perfused and contains dead fragments that blood cannot reach, so antibiotics do not reach them in adequate concentration and immune cells cannot get there either. Raising oxygen in this tissue supports the bacteria-killing action of white blood cells, weakens some anaerobic organisms, and helps new tissue and new vessels form. This is a medically accepted use, but for a specific type: chronic refractory osteomyelitis that has not resolved after proper surgical debridement and culture-directed antibiotics. It is not a treatment for ordinary acute bone infection that resolves with antibiotics, nor for every bone pain, and it is not prescribed before a solid diagnosis. Diagnosing osteomyelitis cannot rest on a superficial swab. **A swab taken from a draining opening on the skin surface is misleading and must not be used to choose the antibiotic.** The correct approach is a culture from bone or deep tissue obtained during surgery or by guided biopsy, together with appropriate imaging such as MRI. The limits are explicit. Hyperbaric oxygen does not sterilise bone, does not remove the need for surgical removal of dead bone, does not replace a prolonged course of targeted antibiotics, does not shorten that course, and does not extract infected metal implants, which frequently need removal or exchange. It also does not open a blocked artery, and where perfusion is poor, arterial assessment and revascularisation form part of the plan. Treatment is a course of repeated sessions over weeks, and the decision is taken by joint assessment between the surgeon and the infectious diseases physician rather than by patient request. The chamber does not suit everyone: untreated pneumothorax is an absolute barrier, active sinus or ear infection postpones the session, certain chemotherapy agents conflict with high-concentration oxygen, uncontrolled epilepsy must be controlled first, pregnancy is excluded except in carbon monoxide poisoning, and claustrophobia needs preparation before entry.
Procedure steps
- 1
Confirming the diagnosis with deep culture and imaging
Before any session the diagnosis is confirmed: appropriate imaging to define how far the infection extends into bone and whether dead fragments or a collection of pus are present, plus a culture from bone or deep tissue taken surgically or by guided biopsy. A superficial swab from a draining opening is not used to choose the drug. Inflammatory markers, blood sugar, nutrition and limb blood flow are all reviewed.
- 2
Surgery and removal of dead bone
The foundation in chronic osteomyelitis is thorough surgical debridement: removing dead bone and inflamed tissue, draining any collection of pus, removing or exchanging infected metal implants, and filling or covering the resulting space with well-perfused tissue where needed. Hyperbaric oxygen is added to this and does not compensate for it, so it cannot be expected to heal dead bone left in place.
- 3
Targeted antibiotics for an adequate period
Antibiotics are prescribed according to culture results, usually for weeks, sometimes starting intravenously and continuing by mouth depending on the case. Completing the full course is a condition for success and it is not shortened because sessions have begun or because pain has eased. Kidney and liver tests and blood counts are monitored during treatment according to the drug used.
- 4
Chamber preparation and the session
Your ears, sinuses and lungs are examined, your medications reviewed, and you are shown in practice how to equalise ear pressure. Fire-safety rules apply: designated clothing, no oils, greasy ointments or perfumes, and no lighters, phones or any electronic device. Pressure is raised gradually, oxygen is breathed for a set period, and pressure is then lowered gradually. **Severe ear pain or bleeding from the ear stops the session.**
- 5
Following response and deciding to continue
Response is judged by what can be measured: pain, temperature, discharge from any opening, inflammatory markers, imaging after an interval, and the state of the surgical wound. Objective improvement is what justifies completing the programme, and if progress stalls the need for further surgery or a change of antibiotic is reconsidered, rather than simply extending sessions without limit.
Before the procedure
Give the doctor the full history: when the infection started, whether it followed a fracture, an operation, a metal implant or a wound, how many operations you have had, which antibiotics you took and for how long, and the results of earlier cultures if available. Bring the reports, because they change the treatment plan. Report all medications including blood thinners, steroids and any chemotherapy, and any epilepsy or seizures, chronic lung disease, previous collapsed lung or ear surgery, and say if you are pregnant or might be. Contact the centre to postpone the session if you develop a cold, blocked nose, or an ear or sinus infection, because a blocked ear is the commonest source of pain inside a chamber, and learn and practise equalisation before entry. Control your blood sugar if you have diabetes and improve your protein intake, as both affect bone healing. Stop smoking. Wear no oil, greasy ointment, perfume or deodorant, and bring no lighter, phone or smart watch into the chamber, as this is a fire-safety rule.
After the procedure
Complete the antibiotic course to the end of the prescribed period even if you feel entirely well, because stopping early is the commonest reason bone infection returns. Keep to your wound-care and dressing appointments exactly as taught, and to the periodic blood tests that monitor the drug's effect on kidneys, liver and blood counts. Do not put more weight on the affected limb than you have been allowed, and follow instructions for any brace or cast. Check your blood sugar after sessions, as it can drop in some patients, and keep your protein intake high. Do not drive while dizzy or with blurred vision, and you may notice a temporary shift in vision over a long programme that usually reverses after it ends. **Seek care immediately for fever or shivering; increasing bone pain; spreading swelling and redness; discharge of pus or a new draining opening; a surgical wound opening up; sudden severe pain or inability to move the limb; numbness, coldness or blue discolouration in it; severe ear pain, bleeding from the ear or hearing loss; shortness of breath or chest pain; or a seizure or twitching.**
Expected duration
A single session usually lasts sixty to one hundred and twenty minutes, plus preparation and observation. Treatment is a programme rather than one visit: typically about twenty to forty sessions or more at roughly one per weekday, running in parallel with a targeted antibiotic course measured in weeks, with periodic reassessment.
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