Colchicine
Colchicine
Ingredients & Drug Type
Colchicine is listed as Other containing Colchicine. A medicine used according to its active ingredient, dosage form, and the patient’s condition.
- Active ingredient
- Colchicine
- Therapeutic class
- Other
- Dosage form
- Tablet
- Strength
- 0.5mg
Dosing
- Max daily
- 2mg في النوبة الحادة
- Frequency
- 2–3 مرات يومياً
- Route
- oral
- Common catalog dose: 0.5mg.
- Frequency: 2–3 مرات يومياً.
- Route: oral.
- Do not exceed: 2mg في النوبة الحادة.
- The final dose depends on diagnosis, age, weight, kidney/liver function, pregnancy status, and other medicines.
- Use the dose written by your doctor or pharmacist; this page is educational and not a personal prescription.
Medical Overview
Colchicine is listed as Other containing Colchicine. A medicine used according to its active ingredient, dosage form, and the patient’s condition.
Colchicine — medicine’s oldest living gout drug and FMF’s lifelong guardian (preventing amyloidosis). Modern low-dose gospel: 1mg then 0.5mg an hour later — full stop (the old “until diarrhea” regimen is history); diarrhea is a dose alarm, not a side effect to endure. Lethal interaction shortlist: clarithromycin/azoles/cyclosporine/grapefruit, statin myopathy stacking, renal-hepatic caution; a handful of tablets can kill a child.
Uses / Indications
- Acute gout attack
- familial Mediterranean fever
- Used for indications selected by a clinician or pharmacist based on diagnosis and the official leaflet.
Side Effects
- Diarrhoea (common)
- abdominal pain
- myopathy
- Side effects vary by active ingredient, dose, and patient factors.
Contraindications
- قصور كلوي أو كبدي شديدان مع مثبطات إنزيمية (الجمع الأخطر)
- اعتلال دم نشط
- وحساسية له. كبار السن الهشون: جرعات مصغرة. الحمل بFMF: يُستمر غالباً بقرار اختصاصي (بياناته مطمئنة) — لا يُوقف ذاتياً.
- Previous allergy to the active ingredient or any component.
Warnings
- قواعده الثلاث غير قابلة للتفاوض: (1) البروتوكول الحديث 1+0.5 فقط — لا «قرص كل ساعتين حتى يتحسن» القديم القاتل
- (2) إسهال = توقف
- (3) **أي مضاد حيوي جديد يمر بسؤال الكولشيسين** (الكلاريثروميسين كمينه الأشهر). لمرضى FMF: انتظامك اليومي يقيك النشوانية الكلوية — لا تفاوض عليه وأخبر كل معالج به. أبعده عن الأطفال (أقراص قليلة تقتل). تابع عبر كلينكس جو.
- Do not start, stop, or change dose without medical advice, especially during pregnancy or chronic disease.
Drug Interactions
- القائمة القاتلة تُحفظ: **كلاريثروميسين وإريثروميسين** (وفيات موثقة بالجمع خصوصاً مع ضعف كلى)
- مضادات الفطور الآزولية
- سيكلوسبورين
- وعصير الجريب فروت — كلها ترفعه خطراً
- ومع الستاتينات: اعتلال عضلي متراكب (أبلغ عن أي ألم عضلي). فيراباميل وديلتيازيم كذلك.
- Tell your clinician or pharmacist about all medicines, supplements, and herbs you use.
Patient Guidance
- Read the patient leaflet.
- Use only as prescribed.
- Ask a pharmacist if anything about use is unclear.
Before Using This Medicine
Tell your clinician before use if you have
- Any previous allergy to this medicine, its class, or any ingredient.
- Pregnancy, breastfeeding, planned pregnancy, or fertility treatment.
- Kidney, liver, heart, stomach ulcer, bleeding, epilepsy, or chronic disease history.
- Regular medicines, supplements, herbal products, or alcohol use.
Seek urgent care if you notice
- Breathing difficulty, face or throat swelling, severe rash, fainting, or chest pain.
- Severe diarrhea, black stools, vomiting blood, yellow eyes, confusion, or unusual bleeding.
- Any symptom that feels severe, new, or rapidly worsening after taking the medicine.
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Storage & Manufacturer
- Storage:
- Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.
Trusted Medical Sources
Use these references to verify official labeling, patient information, therapeutic class, dosing cautions, contraindications, and safety updates.
Common Questions
What is Colchicine?
Colchicine contains Colchicine and is categorized as Other. Its exact use depends on diagnosis and the official product label.
What is the dose of Colchicine?
Catalog dosing information includes: 0.5mg. The personal dose must be confirmed by a doctor or pharmacist.
What warnings matter before using Colchicine?
Check allergies, pregnancy or breastfeeding, chronic disease, and all current medicines before use. Seek urgent care for severe allergy or rapidly worsening symptoms.
How should Colchicine be stored?
Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.