Depakine
Sodium Valproate
Ingredients & Drug Type
Depakine is listed as Neurology containing Sodium Valproate. A medicine used according to its active ingredient, dosage form, and the patient’s condition.
- Active ingredient
- Sodium Valproate
- Therapeutic class
- Neurology
- Dosage form
- Tablet
- Strength
- 500mg
Dosing
- Adult
- 500–2000 mg/day
- Frequency
- حسب وصفة الطبيب
- Route
- oral
- Frequency: حسب وصفة الطبيب.
- Route: oral.
- The final dose depends on diagnosis, age, weight, kidney/liver function, pregnancy status, and other medicines.
- Use the dose written by your doctor or pharmacist; this page is educational and not a personal prescription.
Instructions: التزم بالجرعات بدقة
Medical Overview
Depakine is listed as Neurology containing Sodium Valproate. A medicine used according to its active ingredient, dosage form, and the patient’s condition.
Depakine (valproate) — epilepsy’s broadest spectrum (generalized, myoclonic, absence — its kingdom), plus bipolar and migraine prophylaxis, carrying neurology’s harshest pregnancy warning: 10%+ malformations, 30-40% neurodevelopmental effects — worldwide pregnancy-prevention programmes now gate every prescription for women of childbearing potential. Raises lamotrigine dangerously (halve it), carbapenems crash it, ammonia explains mystery drowsiness; never stop abruptly.
Uses / Indications
- Epilepsy
- migraine
- bipolar disorder
- Used for indications selected by a clinician or pharmacist based on diagnosis and the official leaflet.
Side Effects
- الشائع: زيادة وزن وشهية (من أثقل عائلته)
- رجفة يد جرعية
- تساقط شعر عابر (ينبت مجعداً طريفاً)
- نعاس وغثيان أول الطريق. المخبري المهم: ارتفاع أمونيا (تشوش ونعاس غامضان = فحصها)
- نقص صفيحات جرعي
- وكبد يُفحص (سميته الكبدية القاتلة شبه محصورة بأطفال دون العامين متعددي الأدوية). التهاب بنكرياس نادر (ألم بطن شديد = فوراً).
- Side effects vary by active ingredient, dose, and patient factors.
Contraindications
- **الحمل لعلاج الشقيقة أو ثنائي القطب: ممنوع مطلقاً
- وللصرع: ملاذ أخير بأدنى جرعة إن لم يضبط غيره** — مع فوليك عالٍ ومتابعة تشوهات
- وبرنامج منع الحمل الصارم شرط وصفه لكل قادرة على الإنجاب. أمراض كبد نشطة وسوابق عائلية لسمية كبدية (متلازمات ميتوكوندريا POLG)
- واضطرابات دورة اليوريا.
- Previous allergy to the active ingredient or any component.
Warnings
- Severe contraindication in pregnancy
- Do not start, stop, or change dose without medical advice, especially during pregnancy or chronic disease.
Drug Interactions
- مثبط إنزيمي (عكس أقرانه المحرضين): **يرفع اللاموتريجين خطراً** (يُنصَّف اللاموتريجين معه — طفح SJS)
- يرفع الفينوباربيتال
- والكاربامازيبين يتقاذفان
- والأسبرين يحرره فيسمّمه
- والكاربابينيمات (ميرونيم) تهبطه صادماً (تفاعل مستشفيات شهير). أدوية الصرع تتطلب ضبط اختصاصي دائماً.
- Tell your clinician or pharmacist about all medicines, supplements, and herbs you use.
Patient Guidance
- Read the patient leaflet.
- Use only as prescribed.
- Ask a pharmacist if anything about use is unclear.
Before Using This Medicine
Tell your clinician before use if you have
- Any previous allergy to this medicine, its class, or any ingredient.
- Pregnancy, breastfeeding, planned pregnancy, or fertility treatment.
- Kidney, liver, heart, stomach ulcer, bleeding, epilepsy, or chronic disease history.
- Regular medicines, supplements, herbal products, or alcohol use.
Seek urgent care if you notice
- Breathing difficulty, face or throat swelling, severe rash, fainting, or chest pain.
- Severe diarrhea, black stools, vomiting blood, yellow eyes, confusion, or unusual bleeding.
- Any symptom that feels severe, new, or rapidly worsening after taking the medicine.
Need a prescription or advice about Depakine?
Don't self-medicate. Book an appointment with a Neurology specialist on ClinicsJo — instant and free.
Storage & Manufacturer
- Storage:
- Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.
Trusted Medical Sources
Use these references to verify official labeling, patient information, therapeutic class, dosing cautions, contraindications, and safety updates.
Common Questions
What is Depakine?
Depakine contains Sodium Valproate and is categorized as Neurology. Its exact use depends on diagnosis and the official product label.
What is the dose of Depakine?
Catalog dosing information includes: 500–2000 mg/day. The personal dose must be confirmed by a doctor or pharmacist.
What warnings matter before using Depakine?
Check allergies, pregnancy or breastfeeding, chronic disease, and all current medicines before use. Seek urgent care for severe allergy or rapidly worsening symptoms.
How should Depakine be stored?
Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.