Onglyza
Saxagliptin
Ingredients & Drug Type
Onglyza is listed as Antidiabetic containing Saxagliptin. A diabetes medicine that lowers blood glucose or improves insulin response.
- Active ingredient
- Saxagliptin
- Therapeutic class
- Antidiabetic
- Dosage form
- Tablet
- Strength
- 5mg
Dosing
- Adult
- 5mg مرة يومياً
- Frequency
- مع الوجبات
- Route
- oral
- Frequency: مع الوجبات.
- Route: oral.
- The final dose depends on diagnosis, age, weight, kidney/liver function, pregnancy status, and other medicines.
- Use the dose written by your doctor or pharmacist; this page is educational and not a personal prescription.
Instructions: راقب سكر الدم بانتظام واتبع تعليمات الطبيب
Medical Overview
Onglyza is listed as Antidiabetic containing Saxagliptin. A diabetes medicine that lowers blood glucose or improves insulin response.
Onglyza (saxagliptin) — the third DPP-4: same gentle glucose-dependent mechanism (no hypos alone, weight-neutral) with its own regulatory fingerprint — the SAVOR heart-failure hospitalization signal, making “no established heart failure” its selection rule (sitagliptin or SGLT2s otherwise). Unique family quirk: dose halves to 2.5mg with strong CYP3A4 inhibitors and CrCl<45.
Uses / Indications
- Type 2 diabetes
- Diabetes or insulin resistance depending on the medicine and clinician plan.
Side Effects
- العائلي الهادئ: صداع
- التهاب أنف وبلعوم خفيف
- واضطراب هضمي بسيط. النادر المهم: التهاب بنكرياس (ألم بطن شديد مستمر = إيقاف ومراجعة)
- آلام مفاصل شديدة عكوسة (تحذير العائلة)
- وقصور القلب الموصوف (نهجة وتورم كاحلين مستجدان = مراجعة وتبديل).
- Low blood sugar, stomach upset, appetite or weight changes depending on the medicine.
Contraindications
- النوع الأول والحماض الكيتوني
- حساسية سابقة (وذمة وعائية عائلية نادرة)
- **وقصور القلب القائم: يُتجنب عملياً** (بدائله أذكى). تعديل كلوي: 2.5 ملغ دون تصفية 45.
- Repeated hypoglycemia, ketoacidosis, or severe kidney/liver disease for some agents.
Warnings
- قرص مريح لمرشحه الصحيح: أخبر واصفه بأي قصة قلب أو نهجة جهد قبل بدئه (فرزه الأول)
- وبكورسات الكلاريثروميسين والفطريات (جرعته تُنصَّف معها). ألم بطن علوي شديد لا يهدأ = بنكرياس حتى يثبت العكس. HbA1c كل 3–6 أشهر بوصلة الجدوى — وعائلات أحدث بحماية قلبية-كلوية موثقة تستحق السؤال إن تغيرت حالتك. تابع غددك عبر كلينكس جو.
- Watch for sweating, shaking, intense hunger, and confusion as signs of low blood sugar.
Drug Interactions
- مثبطات CYP3A4 القوية (كيتوكونازول
- كلاريثروميسين) تضاعفه — جرعة 2.5 معها رسمياً (خصوصيته الصيدلانية عائلياً)
- ومع محفزات الأنسولين تُخفض جرعة الشريك هبوطاً.
- May interact with steroids, diuretics, some antibiotics, and alcohol.
Patient Guidance
- Monitor glucose as advised.
- Carry fast sugar if the medicine can cause hypoglycemia.
- Do not change doses during fasting or illness without guidance.
Before Using This Medicine
Tell your clinician before use if you have
- Any previous allergy to this medicine, its class, or any ingredient.
- Pregnancy, breastfeeding, planned pregnancy, or fertility treatment.
- Kidney, liver, heart, stomach ulcer, bleeding, epilepsy, or chronic disease history.
- Regular medicines, supplements, herbal products, or alcohol use.
Seek urgent care if you notice
- Breathing difficulty, face or throat swelling, severe rash, fainting, or chest pain.
- Severe diarrhea, black stools, vomiting blood, yellow eyes, confusion, or unusual bleeding.
- Any symptom that feels severe, new, or rapidly worsening after taking the medicine.
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Storage & Manufacturer
- Storage:
- Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.
Trusted Medical Sources
Use these references to verify official labeling, patient information, therapeutic class, dosing cautions, contraindications, and safety updates.
Common Questions
What is Onglyza?
Onglyza contains Saxagliptin and is categorized as Antidiabetic. Its exact use depends on diagnosis and the official product label.
What is the dose of Onglyza?
Catalog dosing information includes: 5mg مرة يومياً. The personal dose must be confirmed by a doctor or pharmacist.
What warnings matter before using Onglyza?
Check allergies, pregnancy or breastfeeding, chronic disease, and all current medicines before use. Seek urgent care for severe allergy or rapidly worsening symptoms.
How should Onglyza be stored?
Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.