PTU
Propylthiouracil
Ingredients & Drug Type
PTU is listed as Endocrine containing Propylthiouracil. A medicine used according to its active ingredient, dosage form, and the patient’s condition.
- Active ingredient
- Propylthiouracil
- Therapeutic class
- Endocrine
- Dosage form
- Tablet
- Strength
- 50mg
Dosing
- Adult
- 100–300 mg/day
- Frequency
- مرة يومياً
- Route
- oral
- Frequency: مرة يومياً.
- Route: oral.
- The final dose depends on diagnosis, age, weight, kidney/liver function, pregnancy status, and other medicines.
- Use the dose written by your doctor or pharmacist; this page is educational and not a personal prescription.
Instructions: في نفس التوقيت يومياً
Medical Overview
PTU is listed as Endocrine containing Propylthiouracil. A medicine used according to its active ingredient, dosage form, and the patient’s condition.
PTU (propylthiouracil) — the specialist reserve thionamide: dethroned by its 2010 boxed hepatotoxicity warning yet unrivaled in two arenas — first-trimester pregnancy (avoiding carbimazole embryopathy, then switching back) and thyroid storm (unique peripheral T4→T3 blockade). Dual emergency rules memorized: fever+sore throat = same-day CBC; fatigue/jaundice/dark urine = same-day liver panel; thrice-daily dosing demands alarms.
Uses / Indications
- Hyperthyroidism
- especially during pregnancy
- Used for indications selected by a clinician or pharmacist based on diagnosis and the official leaflet.
Side Effects
- كزميله: طفح وحكة
- آلام مفاصل
- واضطراب معدة. **وخطراه المميزان**: سمية كبدية حادة نادرة قد تكون صاعقة (تحذيره الصندوقي — إرهاق واصفرار وبول داكن = إيقاف وفحص فوري)
- وندرة المحببات العائلية (~0.3% — حرارة والتهاب حلق = تعداد اليوم نفسه)
- والتهاب أوعية ANCA بالاستخدام الطويل (خاصيته الثالثة).
- Side effects vary by active ingredient, dose, and patient factors.
Contraindications
- سمية كبدية سابقة منه
- ندرة محببات سابقة من أي ثيوناميد
- وحساسيته الشديدة. الإرضاع: جرعاته المعتدلة مقبولة عائلياً بمتابعة.
- Previous allergy to the active ingredient or any component.
Warnings
- قاعدتا الطوارئ تُحفظان معاً: حرارة والتهاب حلق مفاجئان = تعداد دم اليوم نفسه (العائلية)
- وإرهاق غامض أو اصفرار أو بول داكن = كبد اليوم نفسه (خاصته الصندوقية). حامل بالثلث الأول عليه: التبديل المزدوج المخطط (إليه ثم عنه) ليس تردد طبيبك بل البروتوكول الأذكى عالمياً — اطمئني والتزمي مواعيد الغدد. جرعاته الثلاث تحتاج منبهات. تابعي غددك عبر كلينكس جو.
- Do not start, stop, or change dose without medical advice, especially during pregnancy or chronic disease.
Drug Interactions
- كزميله: مع تعافي الدرقية تُعاير أدوية أُربكت بفرطها (وارفارين
- ديجوكسين
- حاصرات بيتا). لا صدامات كبرى سواها.
- Tell your clinician or pharmacist about all medicines, supplements, and herbs you use.
Patient Guidance
- Read the patient leaflet.
- Use only as prescribed.
- Ask a pharmacist if anything about use is unclear.
Before Using This Medicine
Tell your clinician before use if you have
- Any previous allergy to this medicine, its class, or any ingredient.
- Pregnancy, breastfeeding, planned pregnancy, or fertility treatment.
- Kidney, liver, heart, stomach ulcer, bleeding, epilepsy, or chronic disease history.
- Regular medicines, supplements, herbal products, or alcohol use.
Seek urgent care if you notice
- Breathing difficulty, face or throat swelling, severe rash, fainting, or chest pain.
- Severe diarrhea, black stools, vomiting blood, yellow eyes, confusion, or unusual bleeding.
- Any symptom that feels severe, new, or rapidly worsening after taking the medicine.
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Storage & Manufacturer
- Storage:
- Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.
Trusted Medical Sources
Use these references to verify official labeling, patient information, therapeutic class, dosing cautions, contraindications, and safety updates.
Common Questions
What is PTU?
PTU contains Propylthiouracil and is categorized as Endocrine. Its exact use depends on diagnosis and the official product label.
What is the dose of PTU?
Catalog dosing information includes: 100–300 mg/day. The personal dose must be confirmed by a doctor or pharmacist.
What warnings matter before using PTU?
Check allergies, pregnancy or breastfeeding, chronic disease, and all current medicines before use. Seek urgent care for severe allergy or rapidly worsening symptoms.
How should PTU be stored?
Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.