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Wolff-Parkinson-White Syndrome: Symptoms, Causes, Treatment

متلازمة وولف باركنسون وايت

Quick summary

Wolff–Parkinson–White syndrome involves an extra electrical pathway between an atrium and ventricle that can trigger rapid rhythms. Assessment guides monitoring or appropriate treatment.

Medical disclaimer: This content is for educational purposes only and is not a substitute for consulting a qualified physician. Do not use this information for self-diagnosis or self-treatment.

What is Wolff-Parkinson-White Syndrome?

An asymptomatic preexcitation ECG pattern differs from the symptomatic syndrome. Having no palpitations does not remove the need to assess the pathway’s risk.

Related reading: Types of supraventricular tachycardia.

Symptoms

Abrupt palpitations may accompany dizziness, breathlessness, chest discomfort or fainting. Some people are diagnosed incidentally without symptoms.

Causes

The accessory pathway is present from birth, usually without an identifiable inherited cause. It bypasses normal conduction and may form part of a rapid electrical circuit.

Risk factors

Any age can be affected; male sex and some congenital heart defects are associated. Familial cases occur but are uncommon. The diagnostic label alone does not determine whether ablation is needed.

Diagnosis

Assessment includes ECGs and symptom review, sometimes ambulatory monitoring, exercise testing and heart imaging. An electrophysiology study can characterize the pathway and guide ablation decisions.

Treatment

A specialist selects observation, catheter ablation or suitable medicine. Acute care depends on the rhythm: AV-node-slowing drugs such as adenosine and digoxin are dangerous in preexcited atrial fibrillation.

Complications

Episodes are often controllable, but dangerous rhythms can occur, particularly when rapid atrial fibrillation conducts through the accessory pathway. Individual evaluation establishes risk.

Prevention

There is no proven way to prevent the pathway forming. Keep your ECG report, tell clinicians your diagnosis and discuss medicines and activity with an electrophysiologist; do not self-treat palpitations.

When to see a doctor

Persistent palpitations, chest pain, breathlessness, marked dizziness or fainting requires emergency care. Unresponsiveness with abnormal breathing requires CPR and an available defibrillator.

Scientific references

  1. Wolff-Parkinson-White syndrome — NHS
  2. Other heart rhythm disorders: Wolff-Parkinson-White syndrome — American Heart Association
  3. 2023 ACC/AHA/ACCP/HRS atrial fibrillation guideline: preexcitation syndromes — American College of Cardiology and partner organizations