Tofranil
Imipramine
Ingredients & Drug Type
Tofranil is listed as Psychiatric containing Imipramine. A mental health medicine affecting neurotransmitters, mood, or sleep and usually requiring follow-up.
- Active ingredient
- Imipramine
- Therapeutic class
- Psychiatric
- Dosage form
- Tablet
- Strength
- 25mg
Dosing
- Adult
- 75–150mg/day
- Frequency
- مرة يومياً
- Route
- oral
- Frequency: مرة يومياً.
- Route: oral.
- The final dose depends on diagnosis, age, weight, kidney/liver function, pregnancy status, and other medicines.
- Use the dose written by your doctor or pharmacist; this page is educational and not a personal prescription.
Instructions: تأخذ أسابيع لظهور التأثير الكامل — لا توقفه بدون استشارة
Medical Overview
Tofranil is listed as Psychiatric containing Imipramine. A mental health medicine affecting neurotransmitters, mood, or sleep and usually requiring follow-up.
Tofranil (imipramine) — the 1957 founding antidepressant: undoubted efficacy retired from first line by anticholinergic weight and overdose lethality (the classic fatal childhood poisoning — lock it high). Modern niches: pediatric nocturnal enuresis (after alarm therapy, with baseline ECG, relapse-prone) and expert-tier resistant depression/neuropathic pain. Cardiac conduction respect throughout; never with MAOIs.
Uses / Indications
- Depression
- nocturnal enuresis in children
- Depression, anxiety, psychosis, bipolar disorder, or sleep problems depending on diagnosis.
Side Effects
- الكولينية الثقيلة عائلياً: جفاف فم
- إمساك
- تغيم رؤية
- احتباس بولي (مفارقة مفيدة بسلس الليل!)
- ونعاس ودوخة وقوفية. القلبية: تسرع وإطالة توصيل (تخطيط قبل البدء — إلزامي للأطفال). وزن صاعد
- وتعرق. **جرعته الزائدة قاتلة قلبياً** — أخطر العائلات تسمماً: علب صغيرة بعيدة عن الأيدي.
- Sleepiness, dizziness, dry mouth, appetite/weight change, or sexual side effects depending on the medicine.
Contraindications
- احتشاء حديث واضطرابات توصيل قلبية
- زرق مغلق الزاوية
- احتباس بولي مرضي (عكس سلس الأطفال الوظيفي)
- مثبطات MAO (14 يوماً)
- والهوس. كبار السن: يُتجنب غالباً (تخليط وسقوط وقلب).
- Worsening suicidal thoughts, serious allergy, or unsafe combinations with other psychiatric medicines.
Warnings
- لأهل طفل السلس: هو خيار متأخر لا أول — منبّه الرطوبة يتفوق عليه نجاحاً دائماً (70% مقابل عودة سلس شائعة بعد إيقافه)
- وإن وُصف فتخطيط قلب قبله وجرعة مساء دقيقة **وعلبة مقفلة عالية** (أقراص قليلة تقتل طفلاً — أخطر تسمم دوائي منزلي كلاسيكي). للبالغين: لا إيقاف فجائياً
- ولا قيادة بدايات. احجز أطفال أو نفسية عبر كلينكس جو.
- Do not stop suddenly; some medicines need gradual tapering.
Drug Interactions
- مثبطات CYP2D6 ترفعه خطراً (فلوكسيتين
- باروكستين — جمع يُحسب بدقة)
- الكحول والمهدئات تراكب ثقله
- مضادات الكولين الأخرى تجمع جفافه
- والأدرينالين معه يقفز ضغطاً (تنبيه تخدير الأسنان).
- May interact with alcohol, sedatives, other antidepressants, and some migraine or pain medicines.
Patient Guidance
- Improvement may take several weeks.
- Report sudden mood changes.
- Avoid driving until you know its effect.
Before Using This Medicine
Tell your clinician before use if you have
- Any previous allergy to this medicine, its class, or any ingredient.
- Pregnancy, breastfeeding, planned pregnancy, or fertility treatment.
- Kidney, liver, heart, stomach ulcer, bleeding, epilepsy, or chronic disease history.
- Regular medicines, supplements, herbal products, or alcohol use.
Seek urgent care if you notice
- Breathing difficulty, face or throat swelling, severe rash, fainting, or chest pain.
- Severe diarrhea, black stools, vomiting blood, yellow eyes, confusion, or unusual bleeding.
- Any symptom that feels severe, new, or rapidly worsening after taking the medicine.
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Storage & Manufacturer
- Storage:
- Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.
Trusted Medical Sources
Use these references to verify official labeling, patient information, therapeutic class, dosing cautions, contraindications, and safety updates.
Common Questions
What is Tofranil?
Tofranil contains Imipramine and is categorized as Psychiatric. Its exact use depends on diagnosis and the official product label.
What is the dose of Tofranil?
Catalog dosing information includes: 75–150mg/day. The personal dose must be confirmed by a doctor or pharmacist.
What warnings matter before using Tofranil?
Check allergies, pregnancy or breastfeeding, chronic disease, and all current medicines before use. Seek urgent care for severe allergy or rapidly worsening symptoms.
How should Tofranil be stored?
Store at room temperature away from heat, moisture, and direct sunlight unless the package label says otherwise.