Can autoimmune diseases affect pregnancy?
Yes, autoimmune diseases can affect pregnancy, as these conditions—which occur when the immune system attacks healthy body tissues—may increase health challenges during pregnancy [1]. For women planning a pregnancy, it is essential to consult a doctor in advance to discuss potential risks, evaluate disease stability, and review medications to ensure they are appropriate for pregnancy, as some medications, such as methotrexate, should not be taken when planning a pregnancy [4] [5].
Pre-conception Planning and Medical Follow-up
Pre-conception planning is the cornerstone for women with autoimmune diseases. It is highly recommended to coordinate with your medical team, including a rheumatologist or the physician overseeing your condition, before getting pregnant [4]. The goal of this follow-up is to ensure the disease is as stable as possible before pregnancy, as early and effective management contributes to improving health outcomes for both mother and fetus. For more information on the nature of these disorders, you can review Autoimmune Diseases: Understanding Causes, Diagnosis, and Modern Treatment Options (Arabic).
Managing Medications During Pregnancy
Medication management is a delicate challenge, as one must balance the need to control the disease with the safety of the fetus. You should never stop taking any medication or change dosages without strict medical supervision, as some treatments, such as biologics or certain anti-rheumatic drugs, may need to be stopped or replaced [5]. Your medical team will evaluate your options to minimize inflammation while ensuring your safety and the safety of the pregnancy.
Self-Monitoring and Concerning Signs
During pregnancy, it is necessary to monitor any changes in symptoms that may indicate disease activity. Because these diseases vary in their symptoms—from joint swelling and pain to skin rashes or severe fatigue—constant communication with the doctor allows for proactive adjustments to the treatment plan. If you notice severe or sudden signs, such as intense chest or abdominal pain, or a noticeable deterioration in your general condition, you should consult your specialist or the nearest healthcare center immediately to ensure appropriate intervention, as early diagnosis and regular follow-up reduce the likelihood of serious complications [4].
Dealing with Changes in Health Status
The severity of autoimmune disease symptoms may change during pregnancy and the postpartum period. Maintaining a healthy lifestyle, including balanced nutrition and the use of sunscreen when needed (especially in cases such as lupus), is an important part of self-care [4]. Stay in constant contact with your medical team to discuss any concerns regarding symptoms or body changes, as ongoing medical support helps you navigate this stage effectively.
Medical references
Cite this answer
ClinicsJo Editorial Team. Can autoimmune diseases affect pregnancy? (Sep 13, 2026).
https://clinicsjo.com/en/faq/autoimmune-diseases-and-pregnancy-impact#answerRead the text version with referencesHow to use medical information