When is amniocentesis considered, and what are its benefits and risks?
Amniocentesis is a diagnostic procedure that samples fluid around the fetus under ultrasound guidance. It may be considered after higher-chance screening, scan findings or genetic risk. It is usually performed after fifteen weeks and is an informed choice after discussing benefits, risks and alternatives.
Details
What can it answer?
The laboratory analysis requested determines which conditions can be assessed; sampling does not automatically test for every disease. Genetic counselling helps select tests suited to the family history or concerning finding.
Discussing risk
Small risks include pregnancy loss, fluid leakage and infection. Estimates vary with circumstances, centre experience and singleton or multiple pregnancy. Ask for an estimate relevant to your case rather than one universal percentage. The team also checks blood group and whether rhesus-negative prophylaxis is needed.
After the procedure
Follow the centre’s instructions and contact the team promptly for bleeding, fluid leakage, fever or severe pain. Ask when results are expected and whether further interpretation or testing may be needed. Amniocentesis does not replace other antenatal care.
Related reading: What is NIPT, and can it diagnose Down syndrome?.