Can platelet-rich plasma injections treat knee osteoarthritis or regrow cartilage?
Platelet-rich plasma is prepared from the patient’s blood and is not a stem cell treatment. It may improve knee osteoarthritis pain or function for some people, but evidence varies and does not establish guaranteed cartilage regrowth or benefit for every condition.
Details
Why results cannot be generalised
Studies differ in platelet concentration, preparation, injection schedules and arthritis severity. Possible benefit in one condition does not establish effectiveness for every injury or joint. Pain relief does not necessarily indicate structural cartilage repair.
Its place in a treatment plan
Confirm the diagnosis and discuss exercise, strengthening, weight management and suitable pain relief first. Ask about evidence for your situation, costs, alternatives and how benefit will be assessed. PRP should not delay necessary treatment or assessment of a hot swollen knee where infection is possible.
Risks and preparation
Temporary pain or swelling can occur, and infection or bleeding remains possible despite using the patient’s own blood. Sterile technique and clinical assessment are essential. Disclose medicines and blood disorders; do not stop anticoagulants or pain medicines without professional instructions.
Related reading: What is the difference between total and partial knee replacement?.